Biopharmaceutical Applications

Cyclodextrins

Cyclodextrins are cyclic oligosaccharides that can form inclusion complexes with hydrophobic drug molecules, making them valuable in biopharmaceutical applications. They can protect biologics from degradation, enhance bioavailability, and enable targeted drug delivery. Cyclodextrins play a critical role in improving the process, efficacy, stability, and targeted delivery of biologics drugs, making significant contributions to the field of medicine. Check out our blog post about using cyclodextrins in biopharmaceutical applications.

Parenteral formulations

Emerging trends in excipient selection for safe and effective parenteral formulations

The use of excipients in parenteral formulations is critical in developing safe and effective injectable pharmaceuticals. Recent trends in excipient selection include the focus on biocompatible and biodegradable excipients, advance drug delivery systems, customized excipient solutions, stability and shelf life improvement, regulatory compliance and quality standards, technological advancements, patient-friendly formulations, and compatibility with high-concentration formulations. Staying up to date on these trends helps create safer and more effective products.

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Trehalose

Trehalose is a powerful cryoprotectant that enables cells or tissues to be preserved while maintaining their viability and functionality over long periods of cryopreservation. It is also an essential excipient in the freeze-drying process for biological products.

in Biopharmaceuticals

Biological buffer applications

Biological buffers are organic substances that maintain a solution's pH close to constant. They are used throughout the manufacturing hashtag#process of hashtag#biologics, mainly in upstream (USP) and downstream (DSP) processes. Buffers are utilized in USP because of their ability to help keep culture pH within a certain range and optimize conditions for cell growth.

Mannitol and sorbitol for biological drugs formulation.

In this blog, we discuss the benefits of using polyols as excipients and how they can be used to stabilize biological APIs. We also cover the leading polyols consumed, their solubility in aqueous solutions, and the various functions they serve in formulations. Additionally, we provide information on other products that can be mixed with polyols to create the perfect formulation.